Mexican Meatloaf

This Mexican Meatloaf is one of our family’s favorite comfort food recipes. Studded with ooey gooey cheddar cheese, and flavored with mild salsa, it’s a far cry from the boring, ketchup covered loaf most people are familiar with.  With only five ingredients, it’s also very simple and inexpensive to make! We love to use ground venison for this recipe but when it’s not available, lean ground beef or ground turkey work well too. Quick, inexpensive and delicious? Sign me up for that! 

P.S. Do yourself a favor and be sure not to forget to line your sheet pan with tin foil prior to baking. It saves a ton of hassle and time on clean up! 

Mexican Meatloaf

This flavorful meal is our family's favorite meatloaf recipe. It is super easy and quick to whip up and inexpensive to make too!
5 from 1 vote
Prep Time 5 mins
Cook Time 30 mins
Total Time 35 mins
Course Main Course
Cuisine Mexican
Servings 8


  • Sheet pan
  • large mixing bowl


  • 1 1/2 lbs ground meat of your choice we like venison
  • 1 cup prepared mild salsa divided
  • 3/4 cup breadcrumbs or crushed butter cracker crumbs
  • 5 oz extra sharp cheddar cheese cut into 1/4" cubes
  • 1 egg beaten
  • 1 tsp salt
  • 1/4 tsp pepper


  • Combine all ingredients in a large mixing bowl and mix thoroughly.
  • Cover a sheet pan in tin foil.
  • Form the meat into a flat loaf about 1 foot long and 1 1/2" high. Make sure to get some of the cheese chunks near the top.
  • Bake in a preheated oven at 400 degrees for 30 minutes or until no longer pink inside. Cover the top of the meatloaf with the remaining 1/4 cup of salsa during the last 5 minutes of cooking. If you have picky eaters, you can omit this part or just spread it on some of the loaf as is pictured here.
  • Slice and serve with a side of mashed potatoes and a green vegetable.
Keyword cheese, ground meat, meatloaf, salsa

1 thought on “Mexican Meatloaf”

  1. 5 stars
    My family adored this recipe and I loved that it used ingredients I usually have in hand. This is not your typical meatloaf…… it’s bursting with yummy flavor and great texture. I made some spanish rice on the side and it was very good together. Thank you for sharing this with us!

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